Translation

重要な / 意味のある / 顕著な

Meaning

Significant means important or large enough to be noticed and to matter. It can describe a fact, change, risk, result, or gesture. The trap is using it whenever you mean good; significant means meaningful, not necessarily positive.

Examples

• その判決は業界にとって重要な意味を持ちました。
  The ruling had significant implications for the industry.
• 売上には顕著な増加が見られました。
  There was a significant increase in sales.