Translation

it can't be helped / there's nothing that can be done / unavoidable

Meaning

This is a common Japanese expression used to acknowledge a situation that is beyond your control and cannot be changed. It conveys a sense of acceptance or resignation, often implying that one should stop worrying or trying to alter the unalterable.

Examples

• 雨が降ってきてしまった。もうしょうがない、傘を買いに行こう。
  It started raining. Well, it can't be helped, let's go buy an umbrella.
• 電車が遅延しているらしい。しょうがないから、タクシーで向かいます。
  Apparently the train is delayed. Since there's nothing that can be done, I'll head there by taxi.