angiotensin-converting enzyme
noun
Meaning
A protein produced in the lungs that converts the hormone angiotensin I into the potent vasoconstrictor angiotensin II, thereby increasing blood pressure.
Examples
- The angiotensin-converting enzyme plays a critical role in the body's regulation of fluid balance.
- Patients with hypertension are frequently treated with inhibitors that target the angiotensin-converting enzyme.
Synonyms: ACE, kininase II