angiotensin-converting enzyme

noun

Meaning

A protein produced in the lungs that converts the hormone angiotensin I into the potent vasoconstrictor angiotensin II, thereby increasing blood pressure.

Examples

  • The angiotensin-converting enzyme plays a critical role in the body's regulation of fluid balance.
  • Patients with hypertension are frequently treated with inhibitors that target the angiotensin-converting enzyme.

Synonyms: ACE, kininase II