aneuploidy
noun
Meaning
The presence of an abnormal number of chromosomes in a cell, such as having 45 or 47 chromosomes instead of the standard 46 in humans.
Examples
- Down syndrome is a common form of aneuploidy caused by the presence of an extra copy of chromosome 21.
- Researchers are studying how aneuploidy in cancer cells contributes to tumor growth and drug resistance.
Synonyms: chromosomal abnormality, genomic instability, trisomy, monosomy