aneuploidy

noun

Meaning

The presence of an abnormal number of chromosomes in a cell, such as having 45 or 47 chromosomes instead of the standard 46 in humans.

Examples

  • Down syndrome is a common form of aneuploidy caused by the presence of an extra copy of chromosome 21.
  • Researchers are studying how aneuploidy in cancer cells contributes to tumor growth and drug resistance.

Synonyms: chromosomal abnormality, genomic instability, trisomy, monosomy