amyloid plaque

noun

Meaning

Abnormal deposits of misfolded protein fragments that accumulate between nerve cells in the brain.

Examples

  • The presence of amyloid plaque is a primary hallmark used to diagnose Alzheimer's disease during a post-mortem examination.
  • Researchers are testing new drugs designed to clear amyloid plaque from the brains of patients experiencing early memory loss.

Synonyms: protein deposit, senile plaque, neuritic plaque, amyloid aggregate